Curing the Incurable: Autoimmunity
Vaccine injured, take heart: there's hope.
One of the most insidious “side effects” of vaccine injury, amongst the many and varied other causes, are autoimmune disorders. Everything from autoimmune myocarditis, to psoriasis, to meat allergies caused by the Lone Star Tick, can be traced to disorderly function of the immune system: a protein, be it an endogenous component of the body as in autoimmune disorders, or an otherwise harmless item such as nuts or fruit, the immune system determines that it is a danger to the body, develops B-cell immunity against it, and produces a damaging inflammatory response wherever it is found.
Until now, there have been very limited options for permanent remediation of these disorders. Once the body has developed immunity against any given protein, the only realistic hope of mitigating the inflammatory disorders thusly caused has been one of two bad choices. In one approach, the IgG4 route is exploited: in a strategy most well known for its application in allergy shots, the immune system is continually exposed to the offending protein. As covered in my article on IgG4 - albeit from the perspective of the situation where an IgG4 response is decidedly dangerous and unwanted - such continual exposure to the antigen eventually causes the body to progress through the various classes of immune response it is able to offer, until it eventually decides that the protein is harmless after all, and settles on an IgG4 response. This causes IgG4 antibodies to be produced in response to the antigen, shutting down the immune response, and alleviating the inflammatory response. This comes with the downside of having to endure a prolonged, dangerous and unpleasant immune response until that IgG4 switch is eventually accomplished.
The second option is akin to going after a fly with a bazooka: anti-rejection drugs, such as tacrolimus, can be used to shut down large swathes of the entire immune system. This is obviously a generally bad idea, as it leaves the patient incredibly vulnerable to any opportunistic pathogen that might appreciate a defenseless host in which to replicate. This approach is most frequently used, as the name of this class of drugs may suggest, to prevent rejection of transplanted organs; the foreign organ, not having been naturally grown from the host’s own DNA or comprised of their own tissues, sets off the alarm bells, as aggressively as any infection might. While it is a vital and necessary step in preventing rejection of transplanted organs, the downsides are pretty much as you might expect, essentially leaving the patient with deliberately induced AIDS and dependent on a plethora of pharmaceuticals for survival, possibly and occasionally for life.
A new breakthrough offers us a third, far better option. Rather than forcing a patient to endure a long-term inflammatory response, or deliberately inducing what might as well be AIDS, a new technique now allows doctors to precisely target a specific immune response, against a specific protein, disabling just that particular response. Discussed in this paper, this represents a major breakthrough.
For those who are suffering from any of the myriad of autoimmune disorders induced by the mRNA vaccines - many of which are primarily due to the fact that the furin cleavage site on the spike, being produced within a cell by that cell’s own machinery, enables the spike to protrude through the cell membrane, and thusly cause the cell, and every other cell like it, to be recognized and attacked as a foreign body - this offers a major, and frankly unexpected, ray of hope. Utilizing methods that are usually viewed as problematic - this particular method of immunomodulation is usually seen in cancer, wherein tumor cells will activate the targeted receptors to mitigate an immune attack - if a specific autoreactive antibody can be identified to be the root etiology of a patient’s autoimmune disorder, then this method will allow a therapeutic treatment of that condition, without the non-specific, fly-with-a-bazooka, side-effect heavy approach that necessarily, until now, characterizes the typical treatment regimens. It is also unlikely to create a permanent dependence on the therapy. Quite the opposite, in fact: the authors have noted that the exploitation of this pathway has been observed to successfully induce immune tolerance to the targeted response, permanently shutting it down.
Insofar as autoimmune disease goes, that would constitute what they call a cure.
Take heart, and make sure that victims of vaccine injuries are made aware of this. This could save a lot of lives, and dramatically improve quality of life for others. The implications go far beyond just vaccine injury, too: everything from peanut allergies to congenital autoimmune disorders could conceivably be cured by this development.
The Singularity rolls on!
How It Works
The actual mechanics of how the therapy achieves this miraculous result are quite intriguing, and explaining them will take another brief detour into the weeds of immunology. If you haven’t already done so, I highly recommend reading this article first, for a broad primer on the basic tenets of immunology.